For example, on January 16th, 2022, Facebook page Memes to satisfy the sophisticated gentleman posted a recaptioned meme about McDonald's hash browns that gained over 2,900 reactions and 1,700 shares in one week. Starting in mid-January 2022, the image macro was used as source material for recaptions and edits. On January 21st, 2022, gimmick Twitter account reposted the image, with the post gaining over 9,900 retweets and 137,800 likes in three days. there are a few female brainbots seen throughout the. In the Xbox360, PS3, and Wii Version, they are playable characters. In the DS and PSP version, they were re-programmed by the Blue Tighten, causing them to turn against their own boss (Megamind). They have special abilities such as light display and flight, they also have dog-like personalities. For example, on January 7th, 2022, Tumblr user hades-pal reposted the image, with the post gaining nearly 7,000 likes and reblogs in one month. The Brainbots are Megamind's robot assistants.

Starting in early January 2022, the first image saw viral spread online as a reaction. On December 20th, 2021, iFunny user WinnieThePoohBear posted an alternative version of the macro, with the post gaining over 170 smiles in one month. On December 14th, 2021, iFunny user Weaponized_Retard reposted a reaction image based on the frame, captioned 'No Bitches?,' likely created by an unknown Discord user (shown below). On November 7th, 2021, Instagram user leaderofmoosey posted a video meme that gained over 20,400 likes and 134,000 views in three months (shown below, right). For example, on October 30th, 2021, Twitter user used it in an interaction about Halloween, with the tweet gaining nearly 1,500 likes in three months (shown below, center). Prior to December 2021, the image saw moderate spread online, primarily on Twitter and Discord, where it was used as a reaction. The post gained 53 upvotes in /r/kaiji in three months (shown below, left). On October 28th, 2021, Redditor Even-Face-1256 posted the earliest found fan art based on the image, redrawing it as Itou Kaiji from the Kaiji manga and anime series.

Megamind minion pictures